![]() The recent investigative trend with respect to cancer has continued down a diagnostic path, but has also turned toward concurrent therapy, giving rise to the distinction of MNPs as potential "theranostics". This excitement has been driven in large part by the success of MNPs as contrast agents in magnetic resonance imaging. Interest in utilizing magnetic nanoparticles (MNP) for biomedical applications has increased considerably over the past two decades. With an applied field of 38 kA/m at 980 kHz, tumors could be heated to 60☌ in 2 minutes, durably ablating them with millimeter (mm) precision, leaving surrounding tissue intact.Ĭancer theranostics: the rise of targeted magnetic nanoparticlesĬole, A. Here, we describe use of a magnetic nanoparticle that, with a well-tolerated intravenous dose, achieved a tumor concentration of 1.9 mg Fe/g tumor in a subcutaneous squamous cell carcinoma mouse model, with a tumor to non-tumor ratio > 16. Intravenous injection more faithfully loads tumors, but, so far, it has been difficult achieving the necessary concentration in tumors before systemic toxicity occurs. However, direct intratumoral injections suffer from tumor incongruence and invasiveness, typically leaving undertreated regions, which lead to cancer regrowth. Magnetic nanoparticles heated by an alternating magnetic field could be used to treat cancers, either alone or in combination with radiotherapy or chemotherapy. You may also complete your order by contacting us at 63. Magnetic gold core shell nanoparticles price upgrade#Please enable it or upgrade your browser. International orders: Our regional distributors can provide expedited customs processing and delivery. Our FerroMag™ biocompatible magnetic nanoparticles are unique in the marketĪ significant breakthrough in the pursuit of the medical treatments, contrast agents and sensors of the future.Ĭustom conjugation is also available for Nanogold®, FluoroNanogold™, undecagold or colloidal gold to primary antibodies, peptides, or other molecules.įerroMag™Superparamagnetic iron oxide nanoparticles: Biocompatible for hyperthermia, imaging and materials and many more potential industrial applications Cancer treatment using magnetic hyperthermia**.Excellent heating in an alternating magnetic field.Sized to use EPR to load angiogenic, cancerous tissue. ![]() Extremely low toxicity: MTD50 ≥ 1g Fe/kg in mice*. ![]() Our latest line of nanoparticles are iron-based, yet carefully engineered for both biocompatibility and superparamagnetic properties - and heating in an alternating magnetic field. James F Hainfeld and Hui Huang of Nanoprobes in this video abstract. Magnetic nanoparticles prepared at Nanoprobes have been used to treat cancer with an 80%+ cure rate in mice, using an experimental magnetic hyperthermia therapy (magnetic heating of injected sperparamagnetic nanoparticles). Intravenous magnetic nanoparticle cancer hyperthermia See our paper: magnetic nanoparticle hyperthermia treats cancer in mice FerroMag™ - Iron Oxide (Fe 3O 4) Magnetic Nanoparticles ![]()
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